Goo Taeg Oh Selected Research

KR-31543

12/2012

KR-31543 reduces the production of proinflammatory molecules in human endothelial cells and monocytes and attenuates atherosclerosis in mouse model.

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Goo Taeg Oh Research Topics

Disease

35	Atherosclerosis 01/2022 - 05/2002
16	Inflammation (Inflammations) 11/2022 - 11/2004
9	Obesity 01/2021 - 12/2002
9	Neoplasms (Cancer) 01/2020 - 06/2008
7	Atherosclerotic Plaque (Atheroma) 12/2020 - 10/2004
7	Body Weight (Weight, Body) 10/2020 - 12/2002
6	Cardiovascular Diseases (Cardiovascular Disease) 08/2021 - 08/2011
5	Infections 01/2020 - 01/2002
4	Ischemia 01/2022 - 04/2004
4	Hypoxia (Hypoxemia) 02/2020 - 03/2010
4	Hypertension (High Blood Pressure) 03/2013 - 01/2008
3	Neoplasm Metastasis (Metastasis) 03/2010 - 06/2008
2	Cardiomegaly (Heart Hypertrophy) 01/2022 - 04/2012
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 06/2010
2	Insulin Resistance 01/2021 - 03/2016
2	Fibrosis (Cirrhosis) 01/2021 - 01/2018
2	Type 2 Diabetes Mellitus (MODY) 01/2021 - 03/2016
2	Coronary Artery Disease (Coronary Atherosclerosis) 11/2020 - 01/2020
2	Cysts 10/2020 - 03/2013
2	Vascular Diseases (Vascular Disease) 01/2020 - 03/2013
2	Hypercholesterolemia 10/2018 - 08/2011
2	Asthma (Bronchial Asthma) 10/2018 - 06/2009
2	Rheumatoid Arthritis 10/2018 - 11/2004
2	Hyperlipidemias (Hyperlipidemia) 11/2015 - 07/2014
2	Fatty Liver 11/2015 - 04/2009
2	Necrosis 11/2014 - 04/2012
2	Reperfusion Injury 06/2010 - 04/2004
1	Non-alcoholic Fatty Liver Disease 11/2022
1	Ischemic Stroke 01/2022
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2022
1	Stroke (Strokes) 01/2022
1	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2021
1	Chronic Renal Insufficiency 03/2021
1	Dyslipidemias (Dyslipidemia) 03/2021
1	Weight Gain 01/2021
1	Autosomal Dominant Polycystic Kidney (ADPKD) 10/2020

Drug/Important Bio-Agent (IBA)

16	LipidsIBA 11/2022 - 12/2002
12	Proteins (Proteins, Gene)FDA Link 11/2021 - 03/2006
11	CholesterolIBA 12/2020 - 05/2002
10	CytokinesIBA 03/2021 - 09/2003
10	LDL Receptors (LDL Receptor)IBA 07/2014 - 02/2003
9	ApolipoproteinsIBA 03/2021 - 03/2010
7	Fenofibrate (CiL)FDA LinkGeneric 11/2022 - 12/2002
7	AntioxidantsIBA 01/2022 - 04/2004
7	Apolipoproteins E (ApoE)IBA 03/2021 - 05/2012
6	Pharmaceutical PreparationsIBA 03/2019 - 10/2008
6	PPAR alphaIBA 02/2009 - 12/2002
5	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 11/2022 - 10/2012
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2019 - 04/2004
5	NF-kappa B (NF-kB)IBA 05/2005 - 08/2003
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 08/2011
4	PeroxiredoxinsIBA 01/2022 - 09/2011
4	EnzymesIBA 01/2022 - 08/2011
4	oxidized low density lipoproteinIBA 01/2020 - 10/2004
3	VimentinIBA 01/2022 - 01/2020
3	ResistinIBA 01/2021 - 01/2014
3	Superoxides (Superoxide)IBA 10/2020 - 05/2005
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2020 - 02/2005
3	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 11/2016 - 03/2010
3	LigandsIBA 04/2012 - 10/2008
3	Peptides (Polypeptides)IBA 10/2011 - 10/2008
3	salicylhydroxamic acid (SHAM)IBA 10/2004 - 02/2003
3	Triglycerides (Triacylglycerol)IBA 05/2004 - 12/2002
2	Peroxidase (Myeloperoxidase)IBA 01/2022 - 09/2011
2	RNA (Ribonucleic Acid)IBA 01/2022 - 10/2018
2	EndotoxinsIBA 01/2022 - 02/2014
2	Transcription Factors (Transcription Factor)IBA 01/2020 - 04/2013
2	CatalaseIBA 12/2019 - 09/2011
2	LDL CholesterolIBA 10/2018 - 11/2015
2	Bile Acids and Salts (Bile Acids)IBA 10/2018 - 11/2015
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2018 - 01/2017
2	Adenosine Triphosphatases (ATPase)IBA 12/2017 - 01/2008
2	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 03/2013 - 03/2006
2	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 02/2013 - 05/2012
2	AntibodiesIBA 02/2013 - 11/2006
2	Translationally-Controlled 1 Tumor ProteinIBA 12/2012 - 01/2008
2	Cilostazol (Pletal)FDA LinkGeneric 05/2012 - 05/2005
2	InterleukinsIBA 04/2012 - 09/2003
2	Glutathione Peroxidase GPX1IBA 09/2011 - 06/2010
2	Oxidoreductases (Dehydrogenase)IBA 08/2011 - 05/2004
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 11/2009 - 03/2006
2	Estrogens (Estrogen)FDA Link 02/2009 - 08/2003
2	CalciumIBA 02/2009 - 01/2008
2	LDL Lipoproteins (beta Lipoproteins)IBA 11/2005 - 10/2004
1	Alanine Transaminase (SGPT)IBA 11/2022
1	OsteopontinIBA 01/2022
1	Ferritins (Ferritin)IBA 01/2022
1	Streptozocin (Streptozotocin)FDA Link 01/2022
1	Small Cytoplasmic RNAIBA 01/2022
1	Peroxiredoxin IIIIBA 01/2022
1	hydroxide ionIBA 11/2021
1	Sirolimus (Rapamycin)FDA Link 03/2021
1	Atorvastatin (Lipitor)FDA Link 03/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	Staphylococcal Protein A (Protein A)IBA 11/2020
1	Matrix Metalloproteinases (MMPs)IBA 11/2020
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 11/2020
1	Therapeutic UsesIBA 10/2020
1	p38 Mitogen-Activated Protein KinasesIBA 10/2020

Therapy/Procedure

7	Therapeutics 02/2020 - 06/2010